Other Infertility Tests

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Viral Disease Tests

Rubella titer: Rubella (German measles) can cause heart and hearing defects in a fetus if a pregnant woman contracts the disease during pregnancy. If tests show she is not immune to rubella, the woman should be immunized.

HIV/AIDS: Many doctors also test the woman for the Human Immunodeficiency Virus (HIV), varicella, and hepatitis. If detected, the woman can take precautions to protect her fetus during pregnancy.

Chlamydia and Mycoplasma: These two infectious diseases that may cause infertility. They are diagnosed by taking a sample from the cervix. Chlamydia can infect and damage the fallopian tubes. Mycoplasmas may result in decreased sperm motility, antisperm antibodies, and abnormal egg penetration.

Genetic analysis

The doctor may recommend genetic tests if they are warranted because of the ethnic background or family history of either partner.

Hormone Levels and Ovarian Reserve (blood test)

For most women, fertility declines sometime after age 30, then ends at age 45. For some women, fertility ceases many years earlier, even though they have regular cycles and no signs of menopause. The decline or lack of fertility is reflected in high levels of follicle-stimulating hormone (FSH) or estradiol, as her body attempts to overcome the decline. A blood test early in the woman?s cycle detects the level of FSH. This gives the doctor a general idea of the number of "good eggs" a woman has left in her ovaries (her ovarian reserve).

A blood test should also measure serum prolactin and TSH levels, since abnormalities in these hormones may cause infertility. Other tests may measure thyroid function and levels of leutenizing hormone (LH), progesterone, testosterone, and androstenedione. After basic hormonal tests are performed, the physician reviews the results and may order other diagnostic tests.

Post-Coital Test

The post-coital (after intercourse) test determines whether sperm are able to progress through the woman's cervical mucus. The test is done just before the time of ovulation. The couple has intercourse. Then, 8 to 12 hours later, the physician examines a sample of cervical mucus for the quality and quantity of mucus and for the presence of active sperm.

Endometrial Biopsy
Endometrial Biopsy

Endometrial Biopsy

An endometrial biopsy determines whether the uterine lining (the endometrium) is properly developed to allow a fertilized egg to implant. The physician removes a small sample of tissue from the lining of the uterus 11-13 days after the day of ovulation.

Immunologic Testing

Immunologic factors may play a role in infertility. Testing may be indicated in certain situations.

Diagnostic/Surgical Procedures: Laparoscopy and Hysteroscopy

Based upon the findings of the preliminary infertility tests, the physician may recommend a diagnostic/surgical procedure. The two most commonly performed diagnostic surgical procedures are laparoscopy and hysteroscopy.

Laparoscopy: The physician inserts a viewing telescope called a laparoscope through a small abdominal incision. The laparoscope allows the physician to see the reproductive organs. This procedure requires general anesthesia and usually results in a moderate amount of discomfort after the procedure. The physician may be able to surgically correct some pelvic problems during a laparoscopy.

Hysteroscopy: The physician inserts a viewing telescope called a hysteroscope through the cervix to view and evaluate the uterine cavity. The physician may be able to treat certain physical problems during a hysteroscopy.

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